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Peer Reviewed Studies Adenosine-5'-triphosphate (ATP) Cachexia / Weight Loss

According to a study recently published in the Journal of Clinical Oncology, adenosine 5-triphosphate (ATP) appears to improve energy intake and reduce muscle wasting associated with advanced non-small cell lung cancer patients...Click Here
In conclusion, our study shows that intravenous ATP infusion for 22 to 24 hours is able to restore depleted liver ATP pools in patients with advanced lung cancer to levels similar to or above those in healthy subjects. This effect is most marked in weightlosing lung cancer patients and may contribute to the previously
reported beneficial effects of repeated ATP infusions on the nutritional status of lung cancer patients...
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Cancer-associated loss of appetite and/or weight occurs in more than 50% of all patients with advanced cancer. Weight loss and a decline in functional status are often intimately related. Loss of appetite is one of the most distressing symptoms cancer patients suffer toward the end of life. As noted earlier, multiple agents have been tried to reverse or prevent loss of weight and loss of appetite, but all fall short: none causes weight gain and improvement in appetite for the majority of weight-losing cancer patients with advanced disease...Click Here
In conclusion, our results demonstrate that ATP infusion has marked beneficial effects on the quality of life of patients with advanced non-small-cell lung cancer. In patients who are losing weight, ATP prevents further weight loss and maintains muscle strength of both the upper and the lower extremities.... In contrast to earlier pharmacologic attempts to reverse cancer cachexia, it appears that ATP might be the first agent with beneficial effects on skeletal muscles of cachectic cancer patients...Click Here